摘要 |
<p>The vaccine prepared is comprised of five components: a) inactivated bacteria of the genus Staphylococcus (S. aureus, strain 1A and S. simulans, strain C338); b) exotoxines of S. aureus (strain 1A); c) adjuvant dextran sulfate; d) purified exopolysaccharides of S. aureus (strain C104+) and e) liposomes which contain said exopolysaccharides. The vaccine is comprised of the inoculae A and B. The components a, b and c form the inoculum A and the components d and e form the inoculum B. All the constituent strains were isolated for the vaccine. The utilization of purified exopolysaccharides and of liposomes to immunopotentiate them (inoculum B) make this vaccine efficient against mucous strains of staphylococci, while the application of inoculum A make it efficient against non mucous strains of said genus, as well as against toxines of S. aureus. Said vaccine may be applied to species of ruminants (against mammitis) and it may also be used in human beings.</p> |