| 摘要 |
An agent that inhibits the activity of a lipopolysaccharide binding opsonin is disclosed. The agent has been isolated from plasma and is believed to be a protease that inactivates the opsonin by cleaving it. The agent possesses utility in the treatment of shock and other conditions that may result from the activity of the opsonin in response to host invasion. Diagnostic and therapeutic utilities are proposed, and testing procedures, materials in kit form, recombinant materials and procedures, and pharmaceutical compositions are likewise set forth. |
