Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines.
摘要
<p>A series of novel alkoxypyridin-4-yl and alkoxypyrimidin-4-yl derivatives of indol-3-ylalkylpiperazines of formula I are intended to be useful agents for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites. <CHEM> n</p>
申请公布号
EP0548813(A1)
申请公布日期
1993.06.30
申请号
EP19920121519
申请日期
1992.12.17
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
SMITH, DAVID W.;YOCCA, FRANK D.;YEVICH, JOSEPH P.;MATTSON, RONALD J.;WILLIAMS, ANDREW;RUEDIGER, EDWARD H.;COMBRINK, KEITH DEAN;PEARCE, BRADLEY CLYDE