| 摘要 |
Liquefiable powder compositions are disclosed for the delivery of topical analgesics. In particular, microporous cellulosic powders, such as cellulose acetates or nitrates, are disclosed as high liquid content vehicles for the delivery of liquid analgesic preparations. The resulting powders permit the application of the analgesic preparation by simply rubbing or otherwise applying the formulation onto the skin in such a manner that the powder liquefies and appears to vanish. Upon application, the frangible liquid loaded cellulosic powders break up into minute particles that do not pass easily beyond the initial layers of the skin, but do permit the slow release of the analgesic agent for absorption into the skin.
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