摘要 |
<p>Antiviral agents directed against an immunosuppressive virus are tested on experimental animals which have been transplanted with cells of a donor immune system which are capable of being infected by the immunosuppressive virus and have been infected with the immunosuppressive virus. Experimental animals are used which have an immune system disturbed to such an extent that they, upon transplantation with the donor cells, can experience a fatal graft-versus-host reaction, and which have been transplanted with so large a dose of donor cells that the fatal graft-versus-host reaction occurs except in the experimental animals which are also infected with the immunosuppressive virus.</p> |