GROWTH PROMOTER AND ANIMAL GROWTH PROMOTER CONTAINING LPS

摘要

PURPOSE:To obtain a growth promoter and an animal growth promoter, having high growth promoting effects, usable for a long period and administrable by any of oral or percutaneous route, transcutan bath or injection. CONSTITUTION:A growth promoter is characterized by including at least one of the following lipopolysaccharide (LPS) therein: An LPS capable of providing a content of the LPS, positive to the Limulus test and affording an ED50 of the macrophage activating ability of 0.4-100ng/ml culture solution when sigmoid curves are drawn by using the macrophage activating ability of the LPS activating the TNF productivity of an in vitro cultured macrophage as an index and plotting the macrophage activating ability (%) in the macrophage activating ability providing the TNF production of the macrophage without adding the LPS as 0%, and the macrophage activating ability when the TNF production of the macrophage attains the maximum constant amount as 100% on the coordinate axis versus the content of the LPS positive to the Limulus test at that time expressed on the logarithmic scale on the abscissa axis.