发明名称 METHODS OF TREATING INFLUENZA VIRAL INFECTIONS
摘要 Methods are described for treating an influenza viral infection or associated diseases, disorders or mechanisms in a subject, comprising administering to the subject a therapeutically effective amount of a catecholic butane of the general formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each independently represents a hydrogen, a lower alkyl, a lower acyl, an alkylene, or -OR1 and -OR2 each independently represents an unsubstituted or substituted amino acid residue or pharmaceutically acceptable salt thereof; R3, R4, R5, R6, R10, R11, R12 and R13 each independently represents a hydrogen, or a lower alkyl; and R7, R8 and R9 each independently represents a hydrogen, -OH, a lower alkoxy, a lower acyloxy, an unsubstituted or substituted amino acid residue or pharmaceutically acceptable salt thereof, or any two adjacent groups together may be an alkyene dioxy; with the proviso in certain circumstances that where one of R7, R8 and R9 represents a hydrogen, then -OR1, -OR2 and the other two of R7, R8 and R9 do not simultaneously represent -OH.
申请公布号 US2009155349(A1) 申请公布日期 2009.06.18
申请号 US20070280463 申请日期 2007.02.23
申请人 HELLER JONATHAN DANIEL;LASTER SCOTT MATTHEW;LOPEZ ROCIO ALEJANDRA;FRAZER NEIL 发明人 HELLER JONATHAN DANIEL;LASTER SCOTT MATTHEW;LOPEZ ROCIO ALEJANDRA;FRAZER NEIL
分类号 A61K9/127;A61K9/14;A61K31/05;A61K31/136;A61K31/195;A61K31/225;A61K31/24;A61K31/351;A61K31/405;A61P31/16;C12N5/08;C12N7/06 主分类号 A61K9/127
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