| 摘要 |
The invention is a compound of R or S enantiomers or racemic mixtures of compounds of the formula: <IMAGE> Formula I wherein: (A) X is (i) C1-C24 (ii) C1-C24 alkoxy; (iii) C1-C24 carboamoyloxy; <IMAGE> (iiii) <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> wherein n is an integer from 1 to 25 and m is an integer from 0 to 24 and the sum of n and m is less than or equal to 25; (v) phenyl; (vi) mono-or polysubstituted phenyl substituted with C1-C20 alkoxy, halogen, trifluoromethyl, phenyl, or benzyloxy; (vii) phenoxy; (viii) mono- or polysubstituted phenoxy substituted with C1-C20 alkyl, C1-C20 alkoxy, halogen, trifluoromethyl, phenyl, or benzyloxy; (ix) naphthaloxy; (x) mono- or polysubstituted naphthaloxy substituted with C1-C20 alkyl, C1-C20 alkoxy or halogen; (B) i is an integer from 1 to 3 and j is an integer from 1 to 6; (C) Q is -OR2, <IMAGE> or O-C-R2, wherein R2 is hydrogen, C1-C6 alkyl or C1-C6 alkenyl; (D) Y is the divalent radical <IMAGE> (E) the moiety R3 represents one or more C1-C5 alkyl, C1-C5 alkoxy or halogen substituents of the aromatic ring; (F) the moiety -CH2A may be in the ortho, meta or para position wherein A is the (i) <IMAGE> which are PAF inhibitors.
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