ETHERIC DERIVATIVE OF 4/3H/-QUINAZOLINONE AND A PROCESS FOR THE PREPARATION THEREOF

摘要

An etheric derivative of 4(3H)-quinazolinone namely a fluorinated 3-¢2-(4-biphenylyloxy)ethyl!-4(3H)-quinazoli-none, is produced by reacting said 4(3H)-quinazolinone with the corresponding fluorinated 4-(2-chloroethoxy)biphenyl. The resulting compound and its acid addition salts, especially the hydrochloride, possess substantially higher analgesic activity and lower acute toxicity than aminophenazone, ibuprofen, acetylosalicylic acid and paracetamol.