BINDING OF PLASMODIUM FALCIPARUM-INFECTED ERYTHROCYTES TO CD36

摘要

The invention is a method for inhibiting the binding of Plasmodium Falciparum-infected erythrocytes (IRBCs) to CD36, and a method for selectively killing IRBCs using a toxin-derivatized agent that binds to the CD36 binding site on IRBCs. The reagents used for the methods include (1) CD36, fragments of CD36, CD36 peptides, and antibodies and carbohydrates that bind to the CD36 binding site on IRBCs, and (2) peptides, antibodies, and carbohydrates that bind to the IRBC binding site on CD36.