| 摘要 |
A process for the manufacture of polyamino acids, particularly polyaspartic acid. A solid, particulate, amino acid is fluidized by agitation in a nitrogen atmosphere and heated to a temperature of at least 180 DEG C and maintained at that temperature for a sufficient amount of time to polymerize the amino acid and to drive off water from the heated bed. A degree of agitation sufficient to substantially fluidize the particles is provided and a particle size of no more than 150 microns is maintained throughout the process. The resultant anhydropolyamino acid is then hydrolyzed to a polyamino acid. |
