发明名称 HETEROCYCLIC COMPOUNDS WITH RENIN-INHIBITING PROPERTIES,A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF
摘要 Heterocyclic compounds of the formula (I) <IMAGE> in which the radicals have the following meanings: R<1> is, for example, propyl or isobutyl, R<2> is, for example, phenyl or pyridyl, R<3> is, for example, hydrogen, R<4> is, for example, cyclohexylmethyl, R<5> is, for example, hydrogen or hydroxyl, R<6> is, for example, a radical of the formula (II> (CH2)5-CHR<7>-Z (II> where R<7> is, for example, hydrogen, Z represents a 5- to 7-membered heterocyclic ring and s denotes 0, 1, 2, 3 or 4; are potent renin-inhibiting compounds.
申请公布号 ZA9204521(B) 申请公布日期 1993.02.24
申请号 ZA19920004521 申请日期 1992.06.19
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 HOLGER HEITSCH;HANSJOERG RUBACH;WOLFGANG LINZ;RAINER HENNING;DIETER RUPPERT
分类号 A61K31/495;A61P9/12;A61P43/00;C07D241/10;C07D249/08;C07D401/04;C07D487/04;C07D519/00 主分类号 A61K31/495
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