摘要 |
The invention concerns monoclonal antibodies against the human c-kit receptor which are obtainable from the DSM ACC 2007, DSM ACC 2008 and DSM ACC 2009 cell lines or can be bound to the c-kit receptor in a way which is equivalent to the antibodies produced by the DSM ACC 2007, DSM ACC 2008 or DSM ACC 2009 cell lines. The invention also concerns a method of demonstrating the malignity of tumours of haematopoietic cells, seminomas or small-cell lung carcinomas. In this method, a tissue sample is incubated with at least one monoclonal antibody against the c-kit receptor as proposed by the invention, the presence of bound antibodies subsequently being demonstrated by prior art methods.
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申请人 |
BOEHRINGER MANNHEIM GMBH, 6800 MANNHEIM, DE |
发明人 |
BARTKE, ILSE, DIPL.-BIOL. DR., 8132 TUTZING, DE;KOSTKA, GUENTER, DR., 8000 MUENCHEN, DE;NAUJOKS, KURT, DIPL.-BIOCHEM. DR., 8122 PENZBERG, DE;ULLRICH, AXEL, PROF. DR., 8000 MUENCHEN, DE |