Azolo (1,3,5) triazines as adenosine antagonists.

摘要

A compound of the formula I <CHEM> wherein: A<1> and A<2> are each independently N or CT in which T is hydrogen or (1-4C)alkyl; R<1> and R<2> are each independently hydrogen, (1-6C)alkyl, or (1-4C)alkanoyl; X<1> and X<2> are each independently 0, S or NH; and L is a (3-7C)cycloalkylene group or a (1-8C)alkylene chain optionally interrupted or extended by a group selected from phenylene, phenyleneoxy or oxyphenyleneoxy, the phenylene portion of said group being unsubstituted or substituted by one of halogen, hydroxy and (1-4C)alkoxy, provided that all heteroatoms in the group X<1>-L-X<2> are separated from one another by at least two carbon atoms; or a pharmaceutically acceptable salt thereof, processes for preparing the compounds and pharmaceutical compositions containing them. The compounds are useful as adenosine antagonists.