| 摘要 |
GMP can be prepared in a good yield by converting XMP, ammonia and/or L-glutamine in an aqueous solution using a culture product, cells or their treated product of E. coli having GMP synthetase activity and the ability of converting AMP to ATP in the presence of an energy source other than phosphorus oxides, in the presence of the energy source. GMP can also be prepared in a good yield by converting XMP, ammonia and/or L-glutamine to GMP in an aqueous medium in the presence of ATP using a culture product, cells or their treated product of transformant obtained by using a recombinant DNA of a DNA fragment containing GMP synthetase gene and a vector DNA fragment. The process of using transformant having ATP-reproducing ability is extremely advantageous. |
