| 摘要 |
Process for the preparation of polycyclic ethers of formula <IMAGE> wherein X represents -(CH2)n-, index n stands for integer 0 or 1, symbol R4 designated a hydrogen atom or a methyl radical, R2 identical or different, represent each a hydrogen atom or a lower alkyl radical from C1 to C3 and R designates either a C1 to C6 linear or branched alkyl radical, or a substituted or unsubstituted alkenyl radical having 2 or 3 carbon atoms in the main chain, said alkenyl radical forming a ring such as indicated by the dotted line, which process comprises the cyclization by means of an acidic agent of an unsaturated compound: a) of formula <IMAGE> (IIa) having a double bond in one of the positions indicated by the dotted lines, and wherein index m defines an integer number equal to 1 or 2, symbol R3 stands for a hydrogen atom or a protecting group of the hydroxyl function bound to the oxygen atom and able to dissociate itself from the latter under the reaction conditions, the wavy line represents a C-C bond of cis or trans configuration and index n and symbols R, R2 and R4 are defined as above; or b) of formula <IMAGE> (IIb) wherein symbols R2, R3 and R4, index n and the wavy line are defined as above; or c) of formula <IMAGE> (IIc) wherein symbols R2, R3 and R4, index n and the wavy line are defined as above. Some of the compounds (I) are novel and can be used in the perfume industry.
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