| 摘要 |
Alkali metal salt of meso-2,3-bis(benzylamino)succinic acid, phosgene, and alkali metal hydroxide are reacted under alkaline conditions and in the presence of water and anisole in a multi-phase system to form a multi-phase mixture comprising: (1) a liquid aqueous phase having a pH of at least about 7.5 and comprising an aqueous solution of alkali metal salt of 2-oxo-1,3-dibenzyl-4,5-cis-imidazolidinedicarboxylic acid, and (2) a liquid organic phase. The aqueous solution is acidified to precipitate 2-oxo-1,3-dibenzyl-4,5-cis-imidazolidinedicarboxylic acid.
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