PROCESS FOR TERMINAL HYDROXYLATION OF ETHYL GROUPS ON AROMATIC 5-OR 6-RING HETEROCYCLES

摘要

A microbiological process is disclosed for terminal hydroxylation of ethyl groups substituted on aromatic 5- or 6-ring heterocycles. The hydroxylation is performed with microorganisms which: (a) contain the genes of a Pseudomonas OCT plasmid which form an active alkane monooxygenase, and (b) form no active chromosomal or plasmid-coded alcohol dehydrogenase.