发明名称 USE OF NICOTINIC ANALOGS FOR TREATMENT OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM
摘要 A novel pharmaceutical composition for use as an anti-neurodegenerative agent, comprising anabaseine, DMAB-anabaseine or anabasine in combination wi th a pharmaceutically acceptable carrier, the anabaseine having the general chemical structure: (see formula I) and the anabaseine, DMAB-anabaseine or anabasine also known by the following respective chemical formulae: 2-(3-pyridyl)-3,4,5,6-tetrahydropyridine, 3-[p- (dimethylamino) benzylidene]-3,4,5,6-tetrahydro-2,3'-bypyridine, and 2-(3-pyridyl) piperidin e. A novel method of making an anabaseine-based pharmaceutical composition is also disclosed.
申请公布号 CA2105071(A1) 申请公布日期 1992.09.02
申请号 CA19922105071 申请日期 1992.02.27
申请人 UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 发明人 ZOLTEWICZ, JOHN A.;KEM, WILLIAM R.;MEYER, EDWIN M.
分类号 A61K31/44;A61K31/4427;A61K31/445;A61K31/4545;A61K31/455;A61P21/00;A61P25/00;A61P25/28;A61P43/00;C07D401/04;C07D401/06;(IPC1-7):C07D401/04 主分类号 A61K31/44
代理机构 代理人
主权项
地址
您可能感兴趣的专利