发明名称 |
LIGAND GROWTH FACTORS THAT BIND TO THE ERBB-2 RECEPTOR PROTEIN AND INDUCE CELLULAR RESPONSES |
摘要 |
The present invention relates to erbB-2 ligands and function derivatives thereof which are capable of binding to the erbB-2 transmembrane protein but fail to bind to epidermal growth factor receptor. The present invention further pertains to anti-ligand molecules capable of recognizing and binding to the erbB-2 ligand molecule and to screening assays for such ligands. The present invention additionally relates to uses for the erbB-2 ligand, the anti-ligand molecules and the screening assays. |
申请公布号 |
AU1227792(A) |
申请公布日期 |
1992.08.17 |
申请号 |
AU19920012277 |
申请日期 |
1992.01.13 |
申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
MARC E LIPPMAN;RUTH LUPU |
分类号 |
A61K38/00;A61P35/00;C07K1/00;C07K14/005;C07K14/195;C07K14/475;C07K14/705;C07K16/00;C07K16/22;C12N1/21;C12N15/09;C12N15/12;C12P21/02;G01N33/53;G01N33/566;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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