发明名称 |
TUMOR SUSCEPTIBLE NON-HUMAN ANIMALS |
摘要 |
A desired non-human animal or an animal cell or human cell which contains a predefined, specific and desired alteration in at least one of its two p53 chromosomal alleles, such that at least one of these alleles contains a mutation which alters the expression of the allele, and the other of the alleles expresses either a normal p53 gene product, or comprises an identical or different p53 mutation. |
申请公布号 |
WO9211874(A1) |
申请公布日期 |
1992.07.23 |
申请号 |
WO1992US00295 |
申请日期 |
1992.01.03 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
DONEHOWER, LAWRENCE, A.;BRADLEY, ALLAN;BUTEL, JANET, S.;SLAGLE, BETTY |
分类号 |
A01K67/027;A61K48/00;C07K14/47;C12N5/10;C12N15/09;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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