There are provided chelating agents of formula (I) (wherein n is 0 or 1 and at least one R<1> group comprises a group NR<11>R<14> where one of R<11> and R<14> comprises a cyclic lipophilic group) and metal chelates and salts thereof. The chelates with paramagnetic or heavy metal ions are particularly suited for use as hepatobiliary contrast agents.
申请公布号
WO9211232(A1)
申请公布日期
1992.07.09
申请号
WO1991EP02468
申请日期
1991.12.20
申请人
COCKBAIN, JULIAN, RODERICK, MICHAELSON;NYCOMED AS
发明人
STRANDE, PER;KLAVENESS, JO;RONGVED, PAAL;DUGSTAD, HARALD