3050P/1065A 17318 TITLE OF THE INVENTION EIMERIA ACERVULINA IMMUNOGENS High levels of immunity are achieved in chickens inoculated intramuscularly or orally with E. acervulina extract immunogens. These extracts contain at least 20 polypeptides which induce a protective immune response not only against E. acervulina but also against E. tenella and E. maxima. The resulting immunity prevents intestinal lesions and reduces the number of viable oocysts in vaccinated and challenged birds. One or more of these polypeptides can be used as an immunogen to protect against coccidiosis.
申请公布号
CA1303988(C)
申请公布日期
1992.06.23
申请号
CA19860522726
申请日期
1986.11.12
申请人
MERCK & CO., INC.
发明人
MURRAY, PETER K.;BHOGAL, BALBIR S.;JACOBSON, ETHEL B.;CRANE, MARK S.;SCHMATZ, DENNIS M.;GALUSKA, STEFAN;MACDONALD, THOMAS T.