| 摘要 |
Prodn. of 3-R-7-chloro-8-quinolinecarboxylic acids of formula (I) is effected by direct oxidn. of the corresp. 3-R-7-chloro-8-methylquinoline (II) with HNO3 or NO2 in the presence of H2SO4, a heavy metal cpd. (III) and O2: (In the formulae R = H, Cl or Me.) (III) is a V and/or Co cpd. and is used at a concn. of less than 5 wt.%. The reaction is effected at 150-170 deg. C in 70-85% H2SO4. The O2 is supplied as air. The NOx-contg. off-gas is recycled, opt. after treating with O2 or air.
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