摘要 |
<p>There are disclosed compositions for the amelioration of wrinkles of the skin, an methods for their use. The compositions comprise, as active substance, elastin, at least some of which has a molecular weight of less than 10,000. The compositions may further comprise an agent for reducing corneocyte cohesion of the lower levels of the hyperkeratotic stratum of the skin, such agent being typically an alpha-hydroxy acid. The methods of use of the compositions of the invention may comprise topical application or subcutaneous injection.</p> |