| 摘要 |
Compounds of formula I <CHEM> wherein each R independently is hydrogen or methyl R1 is in 8- or 9-position and represents hydrogen, chloro, fluoro or C 1-3alkyl and R2 represents thienyl, furyl or <CHEM> wherein each Ro represents independently hydrogen, fluoro, chloro, C 1-10alkyl, C 1-10alkoxy or C 1-10alkylthio or one Ro is hydrogen and the other represents tri-(C 1-3alkyl)silyl, trifluoromethyl, phenyl, monochlorophenyl, monofluorophenyl, <CHEM> wherein X, Y, R3, R3' or R4 are as defined herein or two Ro's on adjacent carbon atoms form methylenedioxy. The compounds are indicated for use in treating PAF-mediated bronchocontriction and extravasation |
