发明名称 |
AZASTEROID COMPOUNDS FOR THE TREATMENT OF PROSTATIC HYPERTROPHY, THEIR PREPARATION AND USE |
摘要 |
Compounds of formula (I): (see formula I) (in which: R1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R2 is an aryl-substituted alkyl group, a heterocyclic-substituted alkyl group or a diarylamino group; R3 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or an alkenyl group having from 3 to 6 carbon atoms; and each of the bonds represented by .alpha.-.beta. and .gamma.-.delta. is a carbon-carbon single bond or a carbon-carbon double bond;) and pharmaceutically acceptable salts and esters thereof are useful for the treatment and prophylaxis of prostatic hypertrophy. We also provide processes for their preparation.
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申请公布号 |
CA2054368(A1) |
申请公布日期 |
1992.04.30 |
申请号 |
CA19912054368 |
申请日期 |
1991.10.28 |
申请人 |
KOJIMA, KOICHI;KURATA, HITOSHI;HORIKOSHI, HIROYOSHI;HAMADA, TAKAKAZU |
发明人 |
KOJIMA, KOICHI;KURATA, HITOSHI;HORIKOSHI, HIROYOSHI;HAMADA, TAKAKAZU |
分类号 |
A61K31/56;A61K31/58;A61P13/02;A61P15/00;A61P43/00;C07J73/00;(IPC1-7):C07J73/00 |
主分类号 |
A61K31/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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