| 摘要 |
Compounds of the formula <IMAGE> wherein R<1> is aliphatic or alicyclic hydrocarbyl or optionally substituted phenyl; R<2> is hydrogen or aliphatic hydrocarbyl; R<3> is hydrogen, alkyl, cycloalkyl, optionally substituted phenyl or, with R<4>, R<4> is alkyl, cycloalkyl, optionally substituted phenyl, optionally substituted phenalkyl or, with R<3>, alkylene; or R<2>, R<3> and R<4>, together with the carbon to which each is bond, are adamantyl; and n is 3, 4 or 5; and salts thereof with a base are pharmacologically active. Physiologically-acceptable embodiments are administered, e.g., in the form of an appropriate pharmaceutical composition to warm-blooded animals for protection against and treatment for stomach, intestine, pancreas, bile and liver disorders. Syntheses of pharmacologically-active components, compounding such principles into pharmaceutical compositions and using such principles for preventing and treating the noted disorders are described. |
