发明名称 |
CYCLIC PEPTIDE HAVING CELL PROTECTING ACTION |
摘要 |
The invention relates to cyclic hexapeptides of the general formula I and cyclic dimeric hexapeptides of the general formula II <IMAGE> in which R = Thr or Val; S = Lys or Orn; T = Trp; U = Phe or Phe(p-NHZ); V = D-Pro or D-Ala; W = Phe or Phe(p-NHZ); X = H, Z, COC6H5 or COC6H4(p-N3); and Y = CO(CH2)nCO or CO-O-(CH2-CH2-O)m-CO. A process for preparing these compounds and their use are described. |
申请公布号 |
JPS62263198(A) |
申请公布日期 |
1987.11.16 |
申请号 |
JP19870106472 |
申请日期 |
1987.05.01 |
申请人 |
HOECHST AG |
发明人 |
HORUSUTO KESURAA;ANDOREEASU HAUPUTO;MANFUREETO SHIYUDOKU |
分类号 |
C07K5/10;A61K38/00;A61P1/00;A61P1/16;C07K1/06;C07K1/113;C07K7/06;C07K7/64;C07K14/575;C07K14/655 |
主分类号 |
C07K5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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