RECOMBINANT EXPRESSION VECTORS CAPABLE OF EXPRESSING IMMUNOGENIC MALARIAL ANTIGENS ON THE SURFACE OF SALMONELLA VACCINE STRAINS

摘要

1 HOE 90/B 029 - Ma 846 Recombinant expression vectors capable of expressing immunogenic malarial antigens on the surface of Salmonella vaccine strains Recombinant expression vectors are described which can be used for the expression of the malarial antigens HRPII or SERP or of parts thereof on the surface of gram-negative bacteria being capable of inducing a humoral immune response in mammals. Furthermore, corresponding Salmonella-based vaccines are described.