TRICYCLIC CARBAMATE COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES

摘要

A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of formula (1.0). Also disclosed are novel compounds of formulae (1.1, 1.2 and 1.3). Also disclosed are processes for making 3-substituted compounds of formulae (1.1, 1.2 and 1.3). Further disclosed are novel compounds whic h are intermediates in the processes for making the 3-substituted compounds o f formulae (1.1, 1.2 and 1.3).