POLYPEPTIDE A polypeptide having the cell-attaching activity of fibronectin. The polypeptide has 108 amino acid residues and the formula: . The polypeptide or a biologically active fragment thereof, such as can be employed in the preparation of substrata designed for the attachment of cells thereto. A Cys-residue may optionally be attached at the C-terminus. It can be linked to the surface of a prosthetic device to particularly attract endothelial cells and fibroblastic cells.