发明名称 |
ANTHRACYCLINE COMPOUNDS HAVING ANTI-TUMOUR ACTIVITY, NOVEL INTERMEDIATES FOR THE PREPARATION OF THESE ANTHRACYCLINE COMPOUNDS, AS WELL AS COMPOSITIONS CONTAINING SAID ACTIVE ANTHRACYCLINE COMPOUNDS |
摘要 |
S 5719-9 Can This invention provides novel anti-tumour compounds of the formula wherein R1 and R2 axe hydrogen or together form an alkyl-, alkoxy- or OH-substituted aromatic group, which optionally contains an N atom as a hetero-atom; R is -OOCH3 or -C=C-R4 and R4 is H or trimethylsilyl; and R3 is H or -COCF3; and acid addition salts thereof; as well as compositions containing these compounds.
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申请公布号 |
CA2048510(A1) |
申请公布日期 |
1992.02.17 |
申请号 |
CA19912048510 |
申请日期 |
1991.08.06 |
申请人 |
PHARMACHEMIE B.V. |
发明人 |
SCHEEREN, JOHAN W.;DE BIE, JOANNES F. M.;DE VOS, DIRK |
分类号 |
A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;C07D221/18;C07F7/08;C07H15/24;C07H15/244;C07H15/252;C07H15/26;C07H17/02;(IPC1-7):C07H15/24;C07H23/00 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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