| 发明名称 |
INHIBITION OF MAC-1 RECEPTOR BINDING TO FIBRINOGEN USING D30 HOMOLOGS |
| 摘要 |
The present invention contemplates therapeutic compositions containing a D30 homolog capable of binding to the Mac-1 receptor D30 binding site and inhibiting fibrinogen binding to the Mac-1 receptor via the D30 binding site. Methods of inhibiting Mac-1 receptor binding to any Mac-1 ligand and methods of inhibiting Mac-1 receptor mediated inflammation within a patient by administering a D30 homolog are also contemplated. |
| 申请公布号 |
WO9201464(A1) |
申请公布日期 |
1992.02.06 |
| 申请号 |
WO1991US05096 |
申请日期 |
1991.07.19 |
| 申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
ALTIERI, DARIO;PLOW, EDWARD, F.;EDGINGTON, THOMAS, S. |
| 分类号 |
A61K38/00;A61K38/36;A61K39/395;C07K7/06;C07K7/08;C07K14/00;C07K14/705;C07K14/75;C07K16/00;C07K16/36;C07K16/42;C12N15/02;C12N15/12;C12P21/06;C12P21/08;C12R1/91;G01N33/53;G01N33/566;G01N33/577 |
主分类号 |
A61K38/00 |
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