| 摘要 |
Compositions comprising a radio-protective agent and methods of using such compositions to attenuate or otherwise protect an organism from the adverse effects arising from exposure to ionizing radiation are disclosed. Preferably, the radio-protective agent is an antioxidant and serves to protect the DNA of the organism from damage due to free radicals generated by the ionizing radiation. The methods of use preferably entail determining the timing, duration, and amount of exposure to ionizing radiation and thereby tailoring the administration of the radio-protective agent to protect against the DNA damage expected to arise from such exposure. Potential sources of ionizing radiation include medical imaging (e.g., x-rays, computed tomography, and other techniques in nuclear medicine), radiation therapy, and exposure to radiation in the upper atmosphere (i.e., when flying in an aircraft or space craft). |
