发明名称 NOVEL VITAMIN D ANALOGUES
摘要 <p>The invention relates to compounds of formula (I) in which formula X is hydrogen or hydroxy; Y is oxygen or sulphur or oxidized sulphur (S(O) or S(O2)); R?1 and R2¿, which may be the same or different, stand for hydrogen or C¿1?-C6 hydrocarbyl; or R?1 and R2¿, taken together with the carbon atom (starred in formula I) bearing the group X, can form a C¿3?-C8 carbocyclic ring; Q is a C1-C8 hydrocarbylene diradical. R?3¿ is hydrogen or C¿1?-C6 hydrocarbyl. R?1, R2¿ and/or Q may be optionally substituted with one or more deuterium or fluorine atoms. n is 0 or 1. The present compounds, which find use both in the human and veterinary practice, show an antiinflammatory and immunomodulating effects as well as strong activity in inducing differentiation and inhibiting undesirable proliferation of certain cells, including cancer cells and skin cells.</p>
申请公布号 WO1991015475(A1) 申请公布日期 1991.10.17
申请号 DK1991000091 申请日期 1991.03.22
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