| 摘要 |
<p>Propanamines of general formula (I)
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in which
R1 is an optionally substituted phenyl radical or a 5- or 6-membered monocyclic heteroaryl radical in which the only heteroatom is nitrogen, oxygen or sulphur,
R2 is a lower alkyl radical,
R3 and R4 are a hydrogen atom or a lower alkyl, alkenyl or cycloalkylalkyl radical or, together, they form a saturated heterocyclic ring,
R5 is a cycloalkyl, phenyl or 5- or 6-membered monocyclic heteroaryl radical,
W is =CH-QH, =C[Q-(CH2)n-Q] or C=Q, with Q = O or S, n being equal to 2 or 3, and their addition salts with acids.
<??>These propanamines are used as antidiarrhoetic medications. </p> |
