| 发明名称 |
ENZYMATIC PREPARATION OF 3',4'-ANHYDROVINBLASTINE |
| 摘要 |
3',4'-anhydrovinblastine, a precursor of the anti-tumor alkaloids vincristine and vinblastine, is prepared by the enzymatic coupling of catharanthine and vindoline using an iron-containing compound such as peroxidase optionally in the presence of a peroxide. Substantially enhanced yields are obtained. |
| 申请公布号 |
CA1290270(C) |
申请公布日期 |
1991.10.08 |
| 申请号 |
CA19870543675 |
申请日期 |
1987.08.04 |
| 申请人 |
ALLELIX INC. |
发明人 |
GOODBODY, ANNE E.;ENDO, TSUYOSHI;VUKOVIC, JOHN;MISAWA, MASANARU |
| 分类号 |
C07D519/04;C12N9/08;C12P17/18 |
主分类号 |
C07D519/04 |
| 代理机构 |
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