| 发明名称 |
Oxo-analogs of mevinolin-like antihyper-cholesterolemic agents |
| 摘要 |
Mevinolin-like compounds in which the lactone is opened and the hydroxyl function produced thereby is replaced by an oxo function are potent HMG-CoA reductase inhibitors possessing one less asymmetric center.
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| 申请公布号 |
US5053525(A) |
申请公布日期 |
1991.10.01 |
| 申请号 |
US19860828817 |
申请日期 |
1986.02.13 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
HOFFMAN, WILLIAM F.;LEE, TA J.;STOKKER, GERALD E. |
| 分类号 |
C07C33/46;C07C59/90;C07C205/09;C07D261/08 |
主分类号 |
C07C33/46 |
| 代理机构 |
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