摘要 |
Glutamine-containing peptides, a process for the preparation thereof, and the use thereof Peptides of the structure H-A1-A2-A3-A4-Gln-A6-Lys-Val-A9-A10-NH2 (I) in which A1=Val, Leu A2=Gly, Ser A3=Pro, Hyp A4=Gly, Ser A6=Gly, Ser A9=Leu, Ile and A10=Gly, Ala, and the salts thereof, and a process for the preparation thereof, are described. These peptides act as substrates of blood coagulation factor XIII and can be used for the quantification of this enzyme and for detecting reactions in which activated blood coagulation factor XIII is produced, consumed or inhibited.
|