| 发明名称 |
FORMATION AND RESOLUTION OF DEXIBUPROFEN LYSINE |
| 摘要 |
044/MW25 18032 TITLE OF THE INVENTION: FORMATION AND RESOLUTION OF IBUPROFEN LYSINATE A process is disclosed for the formation and resolution of (S)-ibuprofen-(S)-lysine. The process employs preferential crystallization to separate a pair of diasteromeric salts, (S)-ibuprofen-(S)-lysine and (R)-ibuprofen-(S)-lysine.
|
| 申请公布号 |
CA2033871(A1) |
申请公布日期 |
1991.07.11 |
| 申请号 |
CA19912033871 |
申请日期 |
1991.01.09 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
TUNG, HSIEN-HSIN;WATERSON, STANLEY;REYNOLDS, SCOTT D. |
| 分类号 |
C07B57/00;C07C51/487;C07C57/30;C07C227/42;C07C229/08;C07C229/26;(IPC1-7):C07C51/41;C07C227/34 |
主分类号 |
C07B57/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
