| 摘要 |
NEW MATERIAL:The compound of formula (R<1> is OH or protected OH; R<2> is H,. OH ore protected OH; methyl, ethyl propyl or allyl; n is 1 or 2; the bond containing the dotted line is single or double) or its salt. E X A M P L E : 1 7 - A l l y l - 1, 1 4 - d i h y d r o x y - 1 2 - [ 2 - ( 4 - h y d r o x y - 3 USE:Immunosuppressor and antibiotic agent. PREPARATION:A microbial strain belonging to Streptomyces genus and capable of producing FR-900506 substance, FR-900520 substance and/or FR900525 substance, e.g. Streptomyces tsukubaensis No.9993 (FERM BP-927) is calcutured in a medium and the compound of formula is separated from the cultured product. |
