| 发明名称 |
METHOD OF INHIBITING THE TRANSPORT OF L-GLUTAMATE |
| 摘要 |
A method of inhibiting the transport of a neurotransmitter away from the synapse comprising contacting a neurotransmitter transporter with a compound having structure (I), wherein R<1> = CO2H; -P(OH2); -SO3H; CO2R<3>; P(OR<3>)2; -SO3R; (a); or CONHR<3> in any combination and wherein R<2> = OR<3>, NR<3>2, alkyl, or substituted alkyl and R<3> = alkyl or substituted alkyl. |
| 申请公布号 |
WO9106536(A1) |
申请公布日期 |
1991.05.16 |
| 申请号 |
WO1990US06089 |
申请日期 |
1990.10.24 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
CHAMBERLIN, A., RICHARD;BRIDGES, RICHARD, J.;COTMAN, CARL, W.;STANLEY, MARK, S. |
| 分类号 |
A61K31/40;A61P25/00;A61P25/28;C07D207/12;C07D207/16;C07F9/572 |
主分类号 |
A61K31/40 |
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