发明名称 Method for optical resolution of (+/-)-2-(3-benzoyl)-phenylpropionic acid.
摘要 <p>Optical resolution of (+/-)-2-(3-benzoyl)-phenylpropionic acid is attained efficiently in high yield by the use of a specific optically active amine which is represented by the general formula [I]: &lt;CHEM&gt; [wherein R&lt;1&gt; either stands for a hydrogen atom, a chlorine atom, a bromine atom, a methyl group, or an isopropyl group or participates, as a divalent group, in forming a benzene ring in combination with two carbon atoms adjoining each other in a benzene ring to which the substituent, R&lt;1&gt;, is bonded, R&lt;2&gt; stands for a lower alkyl group, a hydroxymethyl group, an alpha -hydroxybenyl group, or a &lt;CHEM&gt; (R&lt;3&gt; standing for a hydrogen atom, a chlorine atom, a bromine atom, or a methyl group), n for 0 or 1, and * for the center of optical activity).</p>
申请公布号 EP0423467(A2) 申请公布日期 1991.04.24
申请号 EP19900116382 申请日期 1990.08.27
申请人 NISSAN CHEMICAL INDUSTRIES LTD. 发明人 NOHIRA, HIROYUKI;ARAI, KAZUTAKA, C/O NISSAN CHEM. IND. LTD.
分类号 C07C51/487 主分类号 C07C51/487
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