摘要 |
<p>Optical resolution of (+/-)-2-(3-benzoyl)-phenylpropionic acid is attained efficiently in high yield by the use of a specific optically active amine which is represented by the general formula [I]: <CHEM> [wherein R<1> either stands for a hydrogen atom, a chlorine atom, a bromine atom, a methyl group, or an isopropyl group or participates, as a divalent group, in forming a benzene ring in combination with two carbon atoms adjoining each other in a benzene ring to which the substituent, R<1>, is bonded, R<2> stands for a lower alkyl group, a hydroxymethyl group, an alpha -hydroxybenyl group, or a <CHEM> (R<3> standing for a hydrogen atom, a chlorine atom, a bromine atom, or a methyl group), n for 0 or 1, and * for the center of optical activity).</p> |