发明名称 |
Novel peptidase and isomerase inhibitors. |
摘要 |
<p>This invention relates to activated electrophilic ketone analogs of certain peptidase substrates which are useful in inhibiting serine-, carboxylic acid- and metallo- proteolytic senzymes, the inhibition of which will have useful physiological consequences in a variety of disease states.</p> |
申请公布号 |
EP0417721(A2) |
申请公布日期 |
1991.03.20 |
申请号 |
EP19900117461 |
申请日期 |
1990.09.11 |
申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
FLYNN, GARY A.;BEY, PHILIPPE |
分类号 |
C12N9/99;A61K31/215;A61K31/16;A61K31/19;A61K31/195;A61K31/44;A61K31/4402;A61K31/4418;A61K38/00;A61K38/55;A61P7/02;A61P7/06;A61P9/12;A61P17/00;A61P25/00;A61P25/04;A61P29/00;A61P31/12;A61P35/00;A61P43/00;C07C233/47;C07C233/51;C07C233/87;C07C237/22;C07C271/22;C07C279/18;C07C311/42;C07D213/30;C07D213/40;C07K1/113;C07K5/02;C07K5/04;C07K5/06;C07K5/08;C07K5/10;C07K7/06;C07K14/81 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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