| 发明名称 |
N-SUBSTITUTED DIPHENYLPIPERIDINES |
| 摘要 |
Diphenylpiperidines of the formula I wherein R1 is CH, C=CH or CH-CH2 R2 is alkylene or CO-(CH2)n, wherein n is 0 to 11 R3 and R4 are hydrogen. halogen or lower alkoxy Het is pyridyl, pyrimidinyl or imidazolyl and salts thereof with a pharmaceutically acceptable acid possess insulin lowering activity and are useful in the treatment of obesity. |
| 申请公布号 |
CA1281326(C) |
申请公布日期 |
1991.03.12 |
| 申请号 |
CA19860519718 |
申请日期 |
1986.10.03 |
| 申请人 |
HOFFMANN-LA ROCHE (F.) & CO. AKTIENGESELLSCHAFT |
发明人 |
MULLIN, JOHN G., JR.;KIERSTEAD, RICHARD W.;TRISCARI, JOSEPH |
| 分类号 |
C07D401/06;A61K31/44;A61K31/4427;A61K31/445;A61K31/505;A61P3/06;A61P5/38 |
主分类号 |
C07D401/06 |
| 代理机构 |
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代理人 |
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