Oxy- or thio-substituted fatty acid analogs for use in the treatment of retroviral infections.

摘要

Oxy- and thio-substituted fatty acid analog substrates of myristoylating enzymes, which analogues contain an oxygen or sulfur in place of a methylene group in a carbon position from 4 to 13 in the fatty acid chain of a C13-C14 fatty acid or alkyl ester thereof, are useful for the treatment of retroviral infections and in the manufacture of medicaments for the treatment of retroviral infections.