FUSION PROTEINS, THEIR PREPARATION AND USE

摘要

Fusion proteins are obtained in high yields if a mixed oligonucleotide is constructed which codes for the ballast constituent of the fusion protein. The oligonucleotide mixture is introduced in a vector in such a manner that it is functionally linked to a re- gulatory region and to the structural gene for the desired protein. Appropriate host cells are transformed with the plasmid popu- lation obtained in this manner and the clones producing a high yield of code d fusion protein are selected.