| 发明名称 |
2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists |
| 摘要 |
The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) <IMAGE> wherein R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group and at least one of the substituents at positions 3,4 or 5 contains a heterocyclic, heteroaryl or substituted phenylthio moiety.
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| 申请公布号 |
US4996203(A) |
申请公布日期 |
1991.02.26 |
| 申请号 |
US19890362915 |
申请日期 |
1989.06.08 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
BIFTU, TESFAYE;BUGIANESI, ROBERT L.;GIROTRA, NIRINDAR N.;PONPIPOM, MITREE M.;SAHOO, SOUMYA P.;KUO, CHAN H. |
| 分类号 |
A61K31/34;A61K31/341;A61K31/40;A61K31/41;A61K31/415;A61K31/425;A61K31/443;A61K31/4433;A61K31/445;A61K31/54;A61P1/04;A61P9/00;A61P9/02;A61P11/08;A61P13/02;A61P15/00;A61P29/00;A61P37/08;C07D307/12;C07D307/14;C07D307/16;C07D307/18;C07D307/20;C07D307/42;C07D405/04;C07D405/10;C07D405/12;C07D405/14;C07D407/12;C07D409/10;C07D417/04;C07D417/12;C07D521/00 |
主分类号 |
A61K31/34 |
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