| 摘要 |
The invention is directed to a process for the analysis of eukaryotic DNA wherein DNA of an individual is isolated, the DNA is subjected to restriction endonuclease digest, the cleaved DNA is separated by gel electrophoresis, the gel is dried and hybridized with a probe, and the pattern of the DNA is evaluated. The process is characterized in that the probe used is an oligonucleotide which specifically hybridizes to eukaryotic simple tandem repeats having a periodicity of 2 to 4 bases. The process of the invention may be employed for the in vitro diagnosis of genetic defects such as hereditary diseases or for the determination of the genetic interrelationships. |
